Four years is a long time in science. It’s entirely possible that, when I started editing the careers section way back in November 2015, you might have opened Chemistry World for the first time as you started a postdoc, PhD or new job in industry. Now, 44 months later, it’s my last issue. I doubt you are the same person you were then, or even in the same position in life. I know I’m not. Too much has come to pass, both in the world and in my private life, to stand still. And, at the risk of sounding self-indulgent, I’m going to take this one last chance to impart a few pieces of career advice that I’ve picked up along the way before I close this chapter. Be kind.